Micro- and Nanoscale Hydrogel Systems for Drug Delivery and Tissue Engineering

作者：Schwall Christine T; Banerjee Ipsita A^*

来源：Materials, 2009, 2(2): 577-612.

DOI：10.3390/ma2020577

• hydrogel
• micro
• nano
• drug delivery
• tissue engineering
• cancer therapy
• diabetes
• biosensor

The pursuit for targeted drug delivery systems has led to the development of highly improved biomaterials with enhanced biocompatibility and biodegradability properties. Micro-and nanoscale components of hydrogels prepared from both natural and artificial components have been gaining significant importance due to their potential uses in cell based therapies, tissue engineering, liquid micro-lenses, cancer therapy, and drug delivery. In this review some of the recent methodologies used in the preparation of a number of synthetic hydrogels such as poly(N-isopropylacrylamide) (pNIPAm), poly(ethylene glycol) (PEG), poly(ethylene oxide) (PEO), polyvinyl alcohol methylacrylate co-polymers (PVA-MA) and polylactic acid (PLA), as well as some of the natural hydrogels and their applications have been discussed in detail.

• 出版日期2009-6