Direct organocatalytic synthesis of enantiopure succinimides from beta-lactam aldehydes through ring expansion promoted by azolium salt precatalysts

作者：Alcaide Benito^*; Almendros Pedro; Cabrero Gema; Ruiz M Pilar

来源：Chemical Communications, 2007, (45): 4788-4790.

DOI：10.1039/b711473g

A single-step catalytic ring expansion approach from 4-oxoazetidine2-carbaldehydes to enantiopure succinimides has been achieved by the use of a base (DBU) and a thiazolium salt precatalyst.

• 出版日期2007