Development of a Suzuki Cross-Coupling Reaction between 2-Azidoarylboronic Pinacolate Esters and Vinyl Triflates To Enable the Synthesis of [2,3]-Fused Indole Heterocycles

作者：Jana Navendu; Quyen Nguyen; Driver Tom G^*

来源：Journal of Organic Chemistry, 2014, 79(6): 2781-2791.

DOI：10.1021/jo500252e

The scope and limitations of a Suzuki reaction between 2-azidoarylboronic acid pinacolate esters and vinyl triflates are reported. This cross-coupling reaction enables the regioselective synthesis of indoles after a subsequent Rh-2(II)-catalyzed sp(2)-C-H bond amination reaction.

• 出版日期2014-3-21