A Case of Fungus Ball-Type Pansinusitis Due to Fusarium proliferatum

作者：Hashemi Seyed Jamal; Ardehali Mojtaba Mohammadi; Rezaie Sassan; Zibafar Ensieh; Shoar Mohseh Gerami; Rezaei Matehkolaei Ali; Ehteram Hassan; Najafzadeh Mohammad Javad; Nazeri Mehdi^*

来源：Mycopathologia, 2015, 180(3-4): 251-255.

DOI：10.1007/s11046-015-9906-1

• Fusarium proliferatum
• Sinusitis
• Fungus ball
• TEF-1 alpha

Incidence of fungal sinusitis due to the genus Fusarium has increased during the last two decades. We report a case of fungus ball sinusitis with multiple sinuses involvement in an Iranian 21-year-old woman. The patient was diagnosed as having a fungus ball-type sinusitis in computed tomography scan. The sinus biopsy revealed fungal structures on histopathological and direct microscopic examinations and a Fusarium species arose in culture. Partial sequencing of the translation elongation factor 1-alpha identified the isolate as F. proliferatum. Removal of all lesions by endoscopic surgery resulted in a favorable outcome. To the best of our knowledge, this is the first case of F. proliferatum-associated fungus ball which involved multi-sinus and highlights the efficiency of molecular methods for discrimination of fungal agents involved.

• 出版日期2015-10