Adaptation to Climate Across the Arabidopsis thaliana Genome

作者：Hancock Angela M; Brachi Benjamin; Faure Nathalie; Horton Matthew W; Jarymowycz Lucien B; Sperone F Gianluca; Toomajian Chris; Roux Fabrice; Bergelson Joy^*

来源：Science, 2011, 333(6052): 83-86.

DOI：10.1126/science.1209244

Understanding the genetic bases and modes of adaptation to current climatic conditions is essential to accurately predict responses to future environmental change. We conducted a genome-wide scan to identify climate-adaptive genetic loci and pathways in the plant Arabidopsis thaliana. Amino acid-changing variants were significantly enriched among the loci strongly correlated with climate, suggesting that our scan effectively detects adaptive alleles. Moreover, from our results, we successfully predicted relative fitness among a set of geographically diverse A. thaliana accessions when grown together in a common environment. Our results provide a set of candidates for dissecting the molecular bases of climate adaptations, as well as insights about the prevalence of selective sweeps, which has implications for predicting the rate of adaptation.

• 出版日期2011-10-7