A convenient new procedure for converting primary amides into nitriles

作者:Kuo Chun Wei; Zhu Jia Liang; Wu Jen Dar; Chu Cheng Ming; Yao Ching Fa; Shia Kak Shan*
来源:Chemical Communications, 2007, (3): 301-303.
DOI:10.1036/b614061k

摘要

An operationally simple and high-yielding procedure has been developed for the conversion of primary amides to the corresponding nitriles, using ethyl dichlorophosphate/DBU as the mild dehydrating agent.