A simple clinical method to identify women at higher risk of preeclampsia

作者：Viguiliouk Effie; Park Alison L; Berger Howard; Geary Michael P; Ray Joel G^*

来源：Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health, 2017, 10: 10-13.

DOI：10.1016/j.preghy.2017.07.145

• Preeclampsia
• Preterm birth
• Pregnancy
• Prediction
• C-statistic
• Hypertension

An outstanding issue is how to efficiently identify women at high risk of preeclampsia. This retrospective cohort study included 8672 pregnancies at a single centre in Toronto. We tested our simple method presence vs. absence of >1 major (pre-pregnancy BMI > 30 kg/m(2), chronic hypertension, pre-pregnancy diabetes mellitus and assisted reproductive therapy) or >= 2 minor (prior stillbirth, age >40 years, nulliparity, multifetal pregnancy, chronic kidney disease, and SLE) risk factors for PE. The RR of PE was 8.4 (95% CI 5.3-13.2) and the model C-statistic 0.74 (95% CI 0.69-0.79). Further testing of this method elsewhere is warranted.

• 出版日期2017-10