Novel Mono- and Bis(spiro-2-amino-4H-pyrans): Alum-Catalyzed Reaction of 4-Hydroxycoumarin and Malononitrile with Isatins, Quinones, or Ninhydrin

作者：Karimi Ali Reza^*; Sedaghatpour Fahime

来源：Synthesis (Germany), 2010, 2010(10): 1731-1735.

DOI：10.1055/s-0029-1219748

• alum [KAl(SO(4))(2)center dot 12H(2)O]
• spiro-2-amino-4H-pyrans
• 4-hydroxycoumarin

Some new mono- and bis(spiro-2-amino-4H-pyrans) are synthesized by the multicomponent condensation reaction of 4-hydroxycoumarin and malononitrile with isatins, ninhydrin, 9,10-phenanthrenequinone, or acenaphthenequinone. Alum was found to be a suitable and efficient catalyst for this condensation.

• 出版日期2010-5