Digital logic circuit based on two component molecular systems of BSA and salen

作者：Lin Hai-Bin^*; Chen Feng; Guo Hong-Xu

来源：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2018, 191: 435-441.

DOI：10.1016/j.saa.2017.10.031

• Logic circuit
• BSA
• FRET
• Component molecular systems
• Fluorescence

A new fluorescent molecular probe 1 was designed and constructed by combining bovine serum albumin (BSA) and N,N'-bis(salicylidene)ethylenediamine (salen). Stimulated by Zn2+, tris, or EDTAH(2)Na(2), the distance between BSA and salen was regulated, which was accompanied by an obvious change in the fluorescence intensity at 350 or 445 nm based on Forster resonance energy transfer. Moreover, based on the encoding binary digits in these inputs and outputs applying positive logic conventions, a monomolecular circuit integrating one OR, three NOT, and three YES gates, was successfully achieved.

• 出版日期2018-2-15
• 单位闽南师范大学; 福州大学