Acute Kidney Injury in Children An Update on Diagnosis and Treatment

作者：Fortenberry James D^*; Paden Matthew L; Goldstein Stuart L

来源：Pediatric Clinics of North America, 2013, 60(3): 669-+.

DOI：10.1016/j.pcl.2013.02.006

• Acute kidney injury
• Pediatrics
• Continuous renal replacement therapy
• Fluid overload
• Septic shock
• Extracorporeal therapies

The concept and definition of acute kidney injury (AKI) in adults and children has undergone significant change in recent years. Biomarker assessment is aiding in description, defining and understanding timing of AKI. AKI demonstrates unique characteristics in association with sepsis and septic shock, organ dysfunction, and fluid overload. Treatment remains problematic, but growing experience with pediatric continuous renal replacement therapies has improved the delivery of care in children. Increasingly, continuous renal replacement therapy is provided in combination with other extracorporeal technologies, and approaches are advancing to improve combined therapy use.

• 出版日期2013-6