Design and Synthesis of Novel Fused Heterocycles Using 4-Chromanone as Synthon

作者：Ali K A; Abdelhafez N A A; Ragab E A; Ibrahim A A; Amr A E^*

来源：Russian Journal of General Chemistry, 2015, 85(12): 2853-2860.

DOI：10.1134/S107036321512035X

• 4-chromanone
• pyrazole
• pyrimidine
• pyridine

A new series of heterocyclic systems, including azole, azolopyrimidine, and pyridopyrimidine derivatives, attached to 2H-chromene scaffold, was prepared by a convenient procedure through the reactions of (E)-2-dimethylamino-methylene chromanone with different nitrogen binucleophiles. Various substituted chromeno[4,3-b] pyridine derivatives were also prepared through the reactions of (E)-2-dimethylaminomethylene chromanone with a series of active methylene compounds.

• 出版日期2015-12