A novel functionalized pillar[5]arene-based selective amino acid sensor for L-tryptophan

作者:Wei, Tai-Bao*; Chen, Jin-Fa; Cheng, Xiao-Bin; Li, Hui; Han, Bing-Bing; Zhang, You-Ming; Yao, Hong; Lin, Qi*
来源:Organic Chemistry Frontiers, 2017, 4(2): 210-213.
DOI:10.1039/c6qo00569a

摘要

A novel L-tryptophan (L-Trp) fluorescent sensor (BTAP5) based on a functionalized pillar[5] arene has been developed. The sensor BTAP5 exhibits high selectivity and sensitivity (2.83 x 10(-7) M) towards L-Trp in H2O/DMSO (7 : 3, v/v) solution. The recognition mechanism was studied by H-1 NMR, electrospray ionization mass spectrometry and 2D NOESY.