Do zwitterionic species exist in the non-enzymatic peptide bond formation?

作者:Swiderek Katarzyna; Tunon Inaki*; Marti Sergio; Moliner Vicent; Bertran Juan
来源:Chemical Communications, 2012, 48(91): 11253-11255.
DOI:10.1039/c2cc35409h

摘要

The use of proper computational methods and models has allowed answering the controversial question of whether zwitterionic species exist in the mechanism of peptide bond synthesis in aqueous solution. In fact, the different conformations of zwitterionic species open the door to different mechanistic paths.

  • 出版日期2012