Analysis of serum cortisol to predict recovery in paediatric sport-related concussion

作者：Ritchie E V; Emery C; Debert C T^*

来源：Brain Injury, 2018, 32(4): 523-528.

DOI：10.1080/02699052.2018.1429662

• Fluid biomarkers
• neuroendocrine dysfunction
• athletes
• sport-related concussion
• cortisol

Objective: To study the relationship between acute serum cortisol following pediatric sport-related concussion (SRC) and clinical outcome measures of symptom burden and length to return to sport (RTS)Methods: Prospective observational study of ice hockey players ages 11-12 recruited prior to the hockey season. Players sustaining a SRC were assessed by a sports medicine physician completed a child Sport Concussion Assessment Tool-3 (childSCAT-3) and serum cortisol samples.Results: Of 636 ice hockey players enrolled, 41 sustained a SRC. In total, 22 serum cortisol samples were collected, with 14 (63.6%) meeting inclusion criteria. Four players presented with abnormally low cortisol and were more likely to experienced more symptoms (17.8 1.9 vs. 7.5 +/- 6.0) more severe symptoms (28.5 +/- 5.8 vs. 10.2. +/- 8.8) and took longer RTS (23 +/- 13.6 vs. 14.0.7 +/- 7.9.).Conclusion: Paediatric ice hockey players following SRC with abnormally low cortisol may be more susceptible to experiencing increase symptom burden and take longer to return to sport than players with population-based normal cortisol.

• 出版日期2018