An analysis of substrate binding interactions in the heme peroxidase enzymes: A structural perspective

作者：Gumiero Andrea; Murphy Emma J; Metcalfe Clive L; Moody Peter C E; Raven Emma Lloyd^*

来源：Archives of Biochemistry and Biophysics, 2010, 500(1): 13-20.

DOI：10.1016/j.abb.2010.02.015

• Heme
• Peroxidase
• Substrate
• Cytochrome c peroxidase
• Ascorbate peroxidase
• Horseradish peroxidase

The interactions of heme peroxidase enzymes with their substrates have been studied for many years, but only in the last decade or so has structural information begun to appear. This review looks at crystal structures for a number of home peroxidases in complex with a number of (mainly organic) substrates. It examines the nature and location of the binding interaction, and explores functional similarities and differences across the family.

• 出版日期2010-8-1