摘要
Sulfuryl fluoride, SO2F2, has been found to derivatize phenols in all kinds of environments, even those in highly functional molecules. We now report that a solid fluorosulfuryl imidazolium triflate salt delivers the same F-SO2+ fragment to Nu-H acceptor groups in the substrates. However, this triflate salt is a far more reactive fluorosulfurylating agent than SO2F2 and displays selectivity preferences of its own. Moreover, the new azolium triflate reagent reacts once with primary amines and anilines before the reaction stops. On the other hand, with triethylamine and two equivalents of the F-SO2+ donor present, it proceeds on to the bis(fluorosulfuryl)imides in good yieldtwo important conversions that we have never seen with sulfuryl fluoride as the electrophile.
- 出版日期2018-3-1
- 单位中国科学院上海有机化学研究所; 中国科学院大学