科研之友
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摘要
Objective To compare the attentional bias of depressed patients and non-depressed control subjects and examine the effects of age using eye-tracking technology in a free-viewing set of tasks. @@@ Methods Patients with major depressive disorder (MDD) and non-depressed control subjects completed an eye-tracking task to assess attention of processing negative, positive and neutral facial expressions. In this cross-sectional study, the tasks were separated in two types (neutral versus happy faces and neutral versus sad faces) and assessed in two age groups (young' [18-30 years] and middle-aged' [31-55 years]). @@@ Results Compared with non-depressed control subjects (n=75), patients with MDD (n=90) had a significant reduced positive attentional bias and enhanced negative attentional bias irrespective of age. The positive attentional bias in middle-aged' patients with MDD was significantly lower than in young' patients, although there was no difference between the two age groups in negative attentional bias. @@@ Conclusions These results confirm that there are emotional attentional biases in patients with MDD and that positive attentional biases are influenced by age.
