Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen

作者：Al Fatimi Mohamed; Wurster Martina; Schroeder Gudrun; Lindequist Ulrike^*

来源：Journal of Ethnopharmacology, 2007, 111(3): 657-666.

DOI：10.1016/j.jep.2007.01.018

• medicinal plants
• Yemen
• antimicrobial
• cytostatic
• antioxidant

Ninety crude extracts, including dichloromethane, methanol and aqueous extracts from 30 medicinal plants used in the Yemeni ethnomedicine to treat common infections, were screened in vitro for antimicrobial activities against three Gram-positive bacteria and two Gram-negative bacteria, Candida maltosa and five opportunistic human fungal pathogens (two yeasts, three hyphomycetes).
Most of the plants showed antibacterial activities. Extracts from Tamarindus indica flowers and Ficus vasta fruits have been the most active.
Of the 30 plants tested, 13 showed antifungal activity (40%) against one ore more human pathogenic fungi. The strongest inhibition was exhibited by Azima tetracantha (fruits), Sansevieria ehrenbergii (fruits) and Solanum incanum (fruits).
Ten methanol extracts, especially those of Acacia asak barks and Solanum nigrum fruits, showed effective free radical scavenging activities in the DPPH assay.
Remarkable cytotoxic activity against FL-cells was shown only for five plants, among them Plicosepalus curviflorus (stems).

• 出版日期2007-5-22
• 单位河北医科大学