An adult case of medulloblastoma in the cerebellopontine angle extending to the supratentorial area

作者：Cihan Yasemin Benderli^*

来源：Neural Regeneration Research, 2010, 5(21): 1678-1680.

DOI：10.3969/j.issn.1673-5374.2010.21.014

• medulloblastoma
• adult
• cerebellopontine angle
• supratentorial extension

Medulloblastoma is an undifferentiated embryonic neuroepithelial tumor. It is a rare tumor in the central nervous system, with an even rarer occurrence during adulthood. It may develop at an atypical and uncommon site, such as the cerebellopontine angle (CPA), and such tumors rarely present with supratentorial extension. The present study reports an adult case of medulloblastoma in the CPA extending to the supratentorial area. The patient presented with complaints of headache, vertigo, hearing difficulty in the left ear, nausea/vomiting, and unsteady gait. Disequilibrium began 4 weeks earlier. Examination revealed normal cranial nerves, and computed tomography showed a hyperdense lesion, with a heterogeneously enhancing mass, in the left CPA region. The patient underwent a nearly total excision of the lesion in the CPA region. Histopathological examination confirmed medulloblastoma, WHO grade IV. Postoperatively, the patient received radiotherapy and remained asymptomatic for 30 months. However, he received two more surgeries for relapse and progression of medulloblastoma and eventually died. A CPA medulloblastoma with supratentorial extension is relatively rare in the clinic.

• 出版日期2010-11-15