Molecular Iodine-Catalyzed, Mild, Effective, Ecofriendly, Microwave-Assisted, One-Pot Synthesis of 5-Arylmethylidene-2-phenyloxazol-4-ones (Azalactones) Under Solvent-Free Conditions

作者：Reddy M B Madhusudana; Pasha M A^*

来源：Synthetic Communications, 2010, 40(13): 1895-1898.

DOI：10.1080/00397910903162783

• Azalactones
• microwave-assisted synthesis
• molecular iodine
• solvent-free condition

Fourteen azalactones have been synthesized in excellent yields under solvent-free conditions by heating an aldehyde, hippuric acid, and acetic anhydride in the presence of molecular iodine as a catalyst in a microwave oven. The short reaction time, cleaner reaction, and easy workup make this protocol practical and economically attractive.

• 出版日期2010