Complete Hydatidiform Mole and Live Fetus in a Singleton Pregnancy with Confined Placental Mosaicism and Fetomaternal Hemorrhage A Case Report

作者：Baxi Laxmi V^*; Mansukhani Mahesh; Thaker Harshwardhan M; Parravicini Elvira

来源：Journal of Reproductive Medicine, 2014, 59(11-12): 599-602.

• confined placental mosaicism
• fetomaternal hemorrhage
• hydatidfform mole
• molar pregnancy
• molar pregnancy with coexisting live newborn

BACKGROUND: Coexistence of complete mole and a live fetus is uncommon (1:22,000-100,000), more so with euploidy.
CASE: We present a case of a molar pregnancy with a euploid fetus who had close fetal evaluation for second trimester bleeding. The patient presented at 29 weeks' gestation with decreased fetal movements, a result of fetomaternal hemorrhage. She underwent emergency cesarean section and delivered a live infant. By close follow-up and a multidisciplinary approach, the appropriate diagnosis and a favorable outcome were achieved. Both. mother and the child at 5 years of age are doing well.
CONCLUSION: Detailed anatomic and molecular studies demonstrated a complete mole resulting from confined placental mosaicism, with molar tissue showing a single paternal allele at 8/8 'informative loci, all shared with the fetus, thus this coexistent molar pregnancy was not that of a separate conceptus.

• 出版日期2014-12