A cucurbit[8]uril sponge

作者:Ramalingam Vijayakumar; Kwee Sharon K; Ryno Lisa M; Urbach Adam R*
来源:Organic and Biomolecular Chemistry, 2012, 10(43): 8587-8589.
DOI:10.1039/c2ob26774h

摘要

This paper describes a convenient approach to quantitative removal of the synthetic host cucurbit[8]uril (Q8) from aqueous mixtures using a sepharose resin coated in memantine groups to selectively sequester Q8 in the presence of competing hosts and guests. The "Q8 sponge" can separate Q8 from Q6 and reverse the Q8-mediated dimerization of peptides.

  • 出版日期2012