科研之友
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摘要
A new type of ratiometric fluorescent probe capable of detecting Hg2+ ions at nanomolar-concentration level with high selectivity was developed based on an indole-trizole-rhodamine triad and its practicability for intracellular Hg2+ sensing was verified. The as-prepared fluorescent probe is capable of detecting Hg2+ over other competing metal ions including Ag+ with high selectivity. The synergistic effect of Hg2+-assisted conversion of the nonfluorescent ring-closed rhodamine moiety to the highly fluorescent ring-open form as well as the fluorescence signal amplification originating from the Forster resonance energy transfer (FRET) from indole-trizole conjugate to rhodamine moiety contributed to a detection limit of 11 nM of the probe for Hg2+ sensing.
