Different roads to the same destination - The impact of impulsivity on decision-making processes under risk within a rewarding context in a healthy male sample

作者：Dinu Biringer Ramona^*; Nees Frauke; Falquez Rosalux; Berger Moritz; Barnow Sven

来源：Psychiatry Research: Neuroimaging , 2016, 248: 12-22.

DOI：10.1016/j.pscychresns.2016.01.012

• fMRI
• Reward
• Punishment
• Emotional decision-making processes

The results of research about the influences of impulsivity on decision-making in situations of risk have been inconsistent. In this study, we used functional magnetic resonance imaging to examine the neural correlates of decision-making under risk in 12 impulsive, as defined by the Barratt Impulsiveness Scale 11, and 13 normal men. Although both groups showed similar decision-making behavior, neural activation regarding decision-making processes differed significantly. Impulsive persons revealed stronger activation in the (ventro-) medial prefrontal cortex and less deactivation of the orbitofrontal cortex while playing for potential gains. These brain regions might be associated with the emotional components of decision-making processes. Significant differences in brain areas linked to cognitive decision -making components were not found. This activation pattern might be seen as an indication for a hypersensitivity to rewarding cues in impulsive persons and might be linked to the propensity for inappropriate risk taking behavior in persons with more extreme impulsivity levels, especially in situations in which they have a strong emotional involvement in the decision process.

• 出版日期2016-2-28
• 单位上海市精神卫生中心