Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

作者:Takatani Nakase T*; Katayama M; Matsui C; Hanaoka K; van der Vlies A J; Takahashi K; Nakase I*; Hasegawa U*
来源:Molecular Biosystems, 2017, 13(9): 1705-1708.
DOI:10.1039/c7mb00191f

摘要

Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

  • 出版日期2017-9-1