New series of acridines and phenanthrolines: synthesis and characterization

作者：Souibgui Amel; Gaucher Anne; Marrot Jerome; Bourdreux Flavien; Aloui Faouzi; Ben Hassine Bechir^*; Prim Damien

来源：Tetrahedron, 2014, 70(18): 3042-3048.

DOI：10.1016/j.tet.2014.02.067

• Acridine-based architectures
• Phenanthrolines

New series of acridines and phenanthrolines have been prepared from beta-chlorovinyl aldehydes and various aniline derivatives allowing the installation of valuable substituents, such as ketone, nitro or amino groups at the heterocyclic core. X-ray analyses confirmed the structures of acridines and phenanthrolines as well as the presence of partially hydrogenated rings and their crucial impact on the overall shape of the acridine-based architectures. H-1 NMR revealed the helical behaviour of several acridine motives. Comparison of UV data between architectures and influence of number of partially hydrogenated rings is also described.

• 出版日期2014-5-6