科研之友
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摘要
Long associated with increased incidence of stroke,(1,2) migraine has been linked with mechanisms involving the vasculature (vasospasm, arterial dissection, endothelial dysfunction, venous thrombosis), heart (patent foramen ovale), and blood (hypercoagulability).(3) Since cerebral ischemia can induce cortical spreading depression, the physiologic process underlying aura, migraine with aura may theoretically represent a TIA equivalent in a subset of people. In addition to the heightened occurrence of stroke in migraineurs, a growing body of evidence suggests more dire consequences when stroke occurs, with experiments in mice with the familial hemiplegic migraine mutation showing hastened and larger infarct size.(4</SUP)
- 出版日期2015-12-1
