Acute retinal necrosis: factors associated with anatomic and visual outcomes

作者：Iwahashi Shima Chiharu; Azumi Atsushi; Ohguro Nobuyuki^*; Okada Annabelle A; Kaburaki Toshikatsu; Goto Hiroshi; Sonoda Koh Hei; Namba Kenichi; Mizuki Nobuhisa; Mochizuki Manabu

来源：Japanese Journal of Ophthalmology, 2013, 57(1): 98-103.

DOI：10.1007/s10384-012-0211-y

• Acute retinal necrosis
• Retinal detachment
• Visual outcome
• Prophylactic vitrectomy

To examine the factors associated with anatomic and visual outcomes in Japanese patients with acute retinal necrosis (ARN). %26lt;br%26gt;One hundred four patients with ARN who were followed for more than 1 year at nine referral centers were reviewed. Retinal involvement at initial presentation was classified into four groups: zone 1 (posterior pole, n = 22), zone 2 (midperiphery, n = 54), zone 3 (periphery, n = 25), and unknown (n = 3). Forty-eight eyes underwent prophylactic vitrectomy before development of retinal detachment (vitrectomy group); 56 eyes were treated conventionally without prophylactic vitrectomy (observation group). %26lt;br%26gt;The retina was attached in 28 of 48 eyes (58.3 %) in the vitrectomy group and 42 of 56 eyes (75.0 %) in the observation group at the final visit (P = 0.071). At 1 year, 56 eyes (53.8 %) had a best-corrected visual acuity (BCVA) of 20/200 or worse. Multivariate logistic regression analyses identified zone 1 disease (odds ratio = 4.983) and optic nerve involvement (odds ratio = 5.084) as significantly associated with BCVA of 20/200 or worse. Among the zone 3 eyes, significantly (P = 0.012) more eyes in the observation group than in the vitrectomy group had an attached retina. %26lt;br%26gt;Prophylactic vitrectomy did not improve the final BCVA in any eyes. Zone 3 eyes had better outcomes without prophylactic vitrectomy.

• 出版日期2013-1