A novel method of the determination of boron in the presence of a little methanol by discoloring spectrophotometry in pharmaceutical and biological samples

作者：Li Quanmin^*; Zhang Tiantian

来源：Talanta, 2007, 71(1): 296-302.

DOI：10.1016/j.talanta.2006.04.008

• boron
• glycine
• sodium 1,2-naphthoquinone-4-sulfonate
• methanol
• discoloring spectrophotometry

It is the first time that boron is determined in the presence of a little methanol by discoloring spectrophotometry in this paper. A russety product can be formed by the reaction between glycine (Gly) and sodium 1,2-naphthoquinone-4-sulfonate (NQS) in alkaline solution. When boron is added to the solution, the system will be discolored, and the addition of a little methanol will improve the discoloration. Beer's law is obeyed in the range of boron concentrations of 0.86-43.24 mu g ml(-1) at the maximal discoloring wavelength of 382 nm. The equation of linear regression is A = -0.07581-86.79186C (mol 1(-1)), with a linearly correlation coefficient of 0.9979. The detection limit is 0.80 mu g ml(-1) and R.S.D. is 4.2%. The method is successfully applied to the determination of boron in pharmaceutical and biological samples. The average recoveries are in the range of 98.2-104. 1 %. Analytical results obtained with this novel method are satisfactory.

• 出版日期2007-1-15
• 单位河南师范大学