Deep Brain Stimulation: A New Treatment in Mood and Anxiety Disorders

作者：Velasques Bruna^*; Diniz Claudia; Teixeira Silmar; Cartier Consuelo; Peressutti Caroline; Silva Farmy; de Carvalho Marcele; Novaes Aline; Bittencourt Juliana; Nardi Antonio Egidio; Cheniaux Elie; Basile Luis; Cagy Mauricio; Piedade Roberto; Ribeiro Pedro

来源：CNS & Neurological Disorders-Drug Targets, 2014, 13(6): 961-971.

DOI：10.2174/1871527313666140612122929

• Anxiety disorder
• deep brain stimulation
• depression
• obsessive compulsive disorder

This article considered already existing studies about Deep Brain Stimulation in Mood and Anxiety Disorders. In particular, articles regarding Obsessive-Compulsive Disorder and Major Depression were mostly analyzed, due to the lack of researches about other types of Mood and Anxiety Disorders. We have concentrated on the target areas where Deep Brain Stimulation was most commonly applied, and on the effects this measure had on treatment-refractory patients. The obtained results showed that the stimulation of the: nucleus accumbens, subgenual cingulate cortex and ventral capsule/ventral striatum, has a positive influence on the development of the disorders investigated, sometimes showing the complete remission of the symptoms. Although Deep Brain Stimulation was overall found to be a promising and safe treatment for Mood and Anxiety Disorders, there are not enough studies proving its efficacy in wide samples and in the presence of more complex variables.

• 出版日期2014