Assessment of the new nodal classification for cutaneous squamous cell carcinoma and its effect on patient stratification

作者：Brunner Markus^*; Ng Beverly C; Veness Michael J; Clark Jonathan R

来源：Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, 2015, 37(3): 336-339.

DOI：10.1002/hed.23602

• head and neck
• cutaneous squamous cell carcinoma
• TNM

BackgroundThe American Joint Committee on Cancer (AJCC) substantially changed the staging of cutaneous squamous cell carcinoma (SCC) in the seventh edition of its staging manual. Although the system is well established in mucosal SCC, very little data are available on its prognostic value in cutaneous SCC.
MethodsWe conducted a multivariable analysis of 672 patients with metastatic cutaneous SCC from 2 prospective cancer center databases.
ResultsThe differentiation between N1 and N2 subgroups demonstrate little prognostic importance in cutaneous SCC, whereas survival is significantly worse for N3.
ConclusionAlthough the introduction of a unified N system for mucosal SCC and cutaneous SCC has added complexity, it does not translate into optimal distribution and stratification for metastatic cutaneous SCC.

• 出版日期2015-3