科研之友
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摘要
A sensitive and selective biosensor has been developed to detect the hydroxyl radical ((OH)-O-center dot), which was generated through the Fenton reaction. (OH)-O-center dot could oxidatively damage DNA and cleave it into pieces. Based on this, taking [Ru(NH3)(6)](3+) as the electrochemical indicator, (OH)-O-center dot was determined on a gold electrode with self-assembled DNA. The resulting electrochemical biosensor showed a wide linear range of detection from 125 pM to 625 nM with a detection limit of 80 pM and satisfactory selectivity.
- 出版日期2014-8-21
- 单位西南大学
