Stable radical cation salt initiated N-H insertion and related proton-transfer-delay three-component reaction

作者：Huo, Congde^*; Xie, Haisheng; Yang, Caixia; Dong, Jie; Wang, Yajun

来源：Tetrahedron Letters, 2016, 57(20): 2179-2182.

DOI：10.1016/j.tetlet.2016.04.012

• Radical cation
• Triarylaminium salt
• N-H insertion
• Glycine derivative
• Aminal

The N-H insertion reaction forms the single addition product exclusively, and does not require slow addition of the diazo component. More importantly, we present the reaction of anilines with both diazoacetates and azodicarboxylates in the presence of catalytic amounts of triarylaminium salt giving the corresponding complex unsymmetrical aminals in high yields. This is the first example of stable radical cation salt promoted proton-transfer-delay three-component reaction.

• 出版日期2016-5-18
• 单位西北师范大学