Activation of C-F bonds in fluoroarenes by N-heterocyclic carbenes as an effective route to synthesize abnormal NHC complexes

作者：Kim Youngsuk; Lee Eunsung^*

来源：Chemical communications, 2016, 52(72): 10922-10925.

DOI：10.1039/c6cc04896j

IPr (1a) reacts with octafluorotoluene by an unexpected sequential substitution of fluorides in two separate rings. The resulting tetra-substituted imidazolium salt was isolated and elaborated into Ag(I) and Au(I) complexes with a novel abnormal NHC ligand. Both IPr (1a) and IMes (1b) were also found to be moderately reactive by nucleophilic substitution of the aromatic C-F bond in a weakly-activated fluoro-arene, 1-fluoro-4-trifluoromethylbenzene (5).

• 出版日期2016