Adsorption and Release Behavior of BSA and FN on Nanostructural Ti Surface

作者：Shi Jie^*; Feng Bo; Lu Xiong; Wang Jian Xin; Duan Ke; Weng Jie

来源：Journal of Inorganic Materials, 2011, 26(12): 1299-1303.

DOI：10.3724/SP.J.1077.2011.01299

• TiO(2) nanotube
• protein adsorption and release
• bovine serum albumin
• fibronectin

The titanium dioxide (TiO(2)) nanotube arrays with 100 nm diameters on titanium were fabricated by anodic oxidation. The adsorption behaviors of bovine serum albumin (BSA) and fibronectin (FN) onto the nanotube arrays were investigated, and then the protein releases were examined in vitro. Fourier transform infrared spectroscope and Fluorescence microscope were used to qualitative analysis for TiO(2) nanotube arrays surfaces after protein adsorption. Adsorbance of protein was detected with the method of Coomassie brilliant blue G-250. The results showed that TiO(2) nanotube arrays could obviously improve the adsorption, and the adsorption percentage of FN on samples was larger than that of BSA. The release experiment results suggested that the release behaviors of BSA and FN on the nanotube arrays involved the bust release and the gradual release, and the release mechanism was consistent with Fickian diffusion.

• 出版日期2011-12
• 单位西南交通大学