Antidiabetic and antihyperlipidemic effects of &ITArtemisia&IT &ITabsinthium &ITL., &ITCitrullus colocynthis &IT(L.) Schrad. and &ITGymnema sylvestre &IT(Retz.) R.Br. ex Sm. on type II diabetes hyperlipidemic patients

作者：Hassan Mukhtiar; Niazi Aneela Tariq; Khan Samiullah^*; Gul Farzana

来源：Indian Journal of Traditional Knowledge, 2018, 17(2): 233-239.

• Clinical trials
• Diabetes
• Traditional medicine

Artemisia absinthium L., Citrullus colocynthis (L.) Schrad. and Gymnema sylvestre (Retz.) R.Br. ex Sm. have been used in Asian countries for thousands of years to treat diabetes. This study was conducted to evaluate hypoglycemic and antihyperlipidemic effects in type II hyperlipidemic diabetic patients. Study is blind randomized placebo-controlled clinical trials over 40 days. Individuals were divided randomly into 4 groups 1, 2, 3 & 4. Ten individuals were in each group. Group 1 was allocated for G. sylvestre, 2 for A. absinthium, 3 for C. colocynthis and 4 for placebo. Medication (1.0 g/day) was administered for 40 days. From each individual of each group on day 0, 10, 20, 30 and 40 blood samples were collected in fasting condition. Serum glucose values in group 1 dropped most considerably (p < 0.05). Diabetic individuals of all 3 groups as compared to control and placebo group, showed significantly lowered fasting serum glucose level (p < 0.05). Fasting serum triglycerides, cholesterol, HDL-cholesterol and LDL-cholesterol of all 3 groups were not reduced significantly at (p < 0.05) as compared to control and placebo groups. So it may be suggested that a type II diabetic patient can safely be switched from costly conventional antidiabetic medicine to cheap natural products.

• 出版日期2018-4