Bismuth(III) Chloride-Mediated, Efficient, Solvent-Free, MWI-Enhanced Doebner Condensation for the Synthesis of (E)-Cinnamic Acids

作者：Suresh; Kumar Dhruva; Sandhu Jagir S^*

来源：Synthetic Communications, 2010, 40(13): 1915-1919.

DOI：10.1080/00397910903162833

• Bismuth(III) chloride
• (E)-cinnamic acids
• MWI
• solvent free

A bismuth(III) chloride-mediated green process for the production of (E)-cinnamic acid derivatives using microwave irradiation under solvent-free conditions is described. The (E)-cinnamic acids are obtained in excellent yields. This protocol is green because it employs an established environmentally benign procedure, microwave irradiation. Solvent vapor pollution is not there because it is solvent free, and bismuth(III) chloride is an established nontoxic catalyst.

• 出版日期2010