Acute Mediastinitis Associated with Foreign Body Erosion from the Hypopharynx and Esophagus

作者：Liu, Jiajia; Zhang, Xiaoli; Xie, Dinghua; Peng, Anquan; Yang, Xinming^*; Yu, Fenglei; Liu, Deliang

来源：Otolaryngology - Head and Neck Surgery, 2012, 146(1): 58-62.

DOI：10.1177/0194599811425140

• esophageal injury
• foreign bodies
• mediastinal infection
• stents

Objective. Mediastinitis secondary to hypopharyngeal and esophageal foreign bodies is a rare but lethal complication. So far, no literature on a large scale has been reported. This investigation reviewed cases of mediastinitis associated with foreign body ingestion during the past 40 years.
Study Design. Case series with chart review.
Setting. Second Xiangya Hospital, Central South University.
Subjects and Methods. Of 2981 patients with hypopharyngeal and esophageal foreign body impaction included between 1969 and 2010, 93 had complications of acute mediastinitis. Four patients were dead within 4 hours after admission. The rest of the 89 patients underwent surgical drainage. Thirteen underwent primary repair (7 cases with suture, 6 cases with omentum onlay graft), and 9 patients underwent endoscopic stent placement at the same time.
Results. The mean (SD) time between ingestion and initial treatment of patients who developed mediastinitis was 7.72 (1.93) days, compared with 1.92 (1.41) days for those who did not (P<.05). Morbidity was 3.1% and mortality was 30.1% (28/93), but the mortality of every decade has decreased from 38.7% in the 1970s to 8.3% today. Nine cases with local stent were all recovered.
Conclusions. Delay in initiating treatment and intrathoracic esophageal foreign bodies are the main risk factors of mediastinitis secondary to foreign body ingestion. Computed tomography plays an important role in diagnosis and guiding treatments. In conjunction with aggressive surgical debridement and drainage, endoscopic stent placement could be the optimal management for most patients.

• 出版日期2012-1
• 单位中南大学