Association of recreational physical activity with homocysteine, folate and lipid markers in young women

作者：Di Santolo Manuela; Banfi Giuseppe; Stel Giuliana; Cauci Sabina^*

来源：European Journal of Applied Physiology, 2009, 105(1): 111-118.

DOI：10.1007/s00421-008-0880-x

• Female athletes
• Homocysteine
• Folate
• Cholesterol
• Sport activity
• Recreational exercise in women
• Cardiovascular risk

We assessed the influence of recreational physical activity in young healthy women on homocysteine, a potential risk factor for cardiovascular disease (CVD). Participants were 124 23-year-old normal-weight Italian recreational athletes (performing 8.7 +/- A 2.46 h week(-1) exercise) and 116 controls. Median blood homocysteine, folate and lipid markers did not differ between athletes and controls. Elevated homocysteine levels at CVD risk a parts per thousand yen12.0 and a parts per thousand yen15.0 mu mol l(-1) were not different between groups. Continuous homocysteine was inversely related to folate (P < 0.001), positively associated with age (P = 0.009) and creatinine (P = 0.033), but not associated with hours of exercise, body mass index, and lipid markers. Women with folate depletion (< 3.0 mu g l(-1)) were 4.5-fold more likely to have homocysteine a parts per thousand yen15.0 mu mol l(-1). Recreational physical exercise does not adversely impact homocysteine levels among young women. Only low folate significantly increases the risk for hyperhomocysteinemia in young women.

• 出版日期2009-1