Alcohol Impairs Predation Risk Response and Communication in Zebrafish

作者:Oliveira Thiago Acosta; Koakoski Gessi; Kreutz Luiz Carlos; Ferreira Daiane; Santos da Rosa Joao Gabriel; de Abreu Murilo Sander; Vendrametto Giacomini Ana Cristina; Oliveira Ricardo Pimentel; Fagundes Michele; Piato Angelo Luis; Barreto Rodrigo Egydio; Gil Barcellos Leonardo Jose
来源:PLos One, 2013, 8(10): e75780.
DOI:10.1371/journal.pone.0075780

摘要

The effects of ethanol exposure on Danio rerio have been studied from the perspectives of developmental biology and behavior. However, little is known about the effects of ethanol on the prey-predator relationship and chemical communication of predation risk. Here, we showed that visual contact with a predator triggers stress axis activation in zebrafish. We also observed a typical stress response in zebrafish receiving water from these conspecifics, indicating that these fish chemically communicate predation risk. Our work is the first to demonstrate how alcohol effects this prey-predator interaction. We showed for the first time that alcohol exposure completely blocks stress axis activation in both fish seeing the predator and in fish that come in indirect contact with a predator by receiving water from these conspecifics. Together with other research results and with the translational relevance of this fish species, our data points to zebrafish as a promising animal model to study human alcoholism.

  • 出版日期2013-10-7