Novel biomarkers for patients with idiopathic acute anterior uveitis: neutrophil to lymphocyte ratio and platelet to lymphocyte ratio

作者：Ozgonul Cem; Sertoglu Erdim; Ayyildiz Onder; Mumcuoglu Tarkan; Kucukevcilioglu Murat; Gokce Gokcen; Durukan Ali Hacan

来源：International Journal of Ophthalmology, 2017, 10(2): 262-266.

DOI：10.18240/ijo.2017.02.13

• C-reactive protein
• inflammation
• neutrophil
• lymphocyte
• platelet
• uveitis

AIM: To assess the levels of the neutrophil to lymphocyte ratio (N/L) and the platelet to lymphocyte ratio (P/L) in patients with idiopathic acute anterior uveitis (AAU) and to compare with healthy controls.
METHODS: Thirty-six male patients with idiopathic AAU and 36 male healthy subjects were enrolled in this retrospective study. Complete ophthalmological examination and complete blood count measurements results of all subjects were evaluated.
RESULTS: There was a significant difference in N/L and P/L between idiopathic AAU and control groups (P=0.006, P=0.022). Also, correlation analysis revealed a significant correlation between C-reactive protein (CRP) and N/L (P= 0.002; r=0.461).
CONCLUSION: Our study for the first time provides evidence of N/L and P/L may be useful biomarkers in patients with idiopathic AAU. N/L is correlated with CRP, so it can be a useful biomarker to predict the prognosis in idiopathic AAU.

• 出版日期2017-2-18
• 单位中国人民解放军军事医学科学院