n-3 Polyunsaturated fatty acids and mast cell activation

作者:Wang Xiaofeng; Kulka Marianna*
来源:Journal of Leukocyte Biology, 2015, 97(5): 859-871.
DOI:10.1189/jlb.2RU0814-388R

摘要

Mast cells are known to play a vital role in the development of inflammation in allergic responses. Recent studies have indicated that mast cell activation could be modulated by n-3 PUFAs, which have a wide range of well-documented health benefits. In our review, we summarize the recent findings and potential mechanisms of the effect of n-3 PUFAs on mast cell activation. This knowledge could provide new strategies for the development of therapeutic interventions for diseases mediated by mast cells.

  • 出版日期2015-5
  • 单位Saskatchewan