Study of aza-cyclization of alpha,beta-unsaturated carbonyl moieties and synthetic application to hexahydroapoerysopine

作者：Kim Hee Dong; Kim Guncheol^*

来源：Tetrahedron Letters, 2013, 54(13): 1765-1767.

DOI：10.1016/j.tetlet.2013.01.093

• Aza-cyclization
• Polycyclic alkaloid
• Hexahydroapoerysopine
• Azepine

Aza-cyclization of alpha,beta-unsaturated carbonyl moieties with free amine has been studied. An azepine alkaloid, hexahydroapoerysopine, has been synthesized from an enone-ester in a concise manner through the aza-cyclization followed by reductions.

• 出版日期2013-3-27