A novel superparamagnetic surface molecularly imprinted nanoparticle adopting dummy template: An efficient solid-phase extraction adsorbent for bisphenol A

作者：Lin Zhenkun; Cheng Wenjing; Li Yanyan; Liu Zhiren; Chen Xiangping; Huang Changjiang^*

来源：Analytica Chimica Acta, 2012, 720: 71-76.

DOI：10.1016/j.aca.2012.01.020

• Molecularly imprinted polymer
• Superparamagnetic
• Dummy template
• Solid-phase extraction
• Bisphenol A

Leakage of the residual template molecules is one of the biggest challenges for application of molecularly imprinted polymer (MIP) in solid-phase extraction (SPE). In this study, bisphenol F (BPF) was adopted as a dummy template to prepare MIP of bisphenol A (BPA) with a superparamagnetic core-shell nanoparticle as the supporter, aiming to avoid residual template leakage and to increase the efficiency of SPE. Characterization and test of the obtained products (called mag-DMIP beads) revealed that these novel nanoparticles not only had excellent magnetic property but also displayed high selectivity to the target molecule BPA. As mag-DMIP beads were adopted as the adsorbents of solid-phase extraction for detecting BPA in real water samples, the recoveries of spiked samples ranged from 84.7% to 93.8% with the limit of detection of 2.50 pg mL(-1), revealing that mag-DMIP beads were efficient SPE adsorbents.

• 出版日期2012-3-30
• 单位温州医科大学