An fMRI Study of Local Synchronization in Different Subfrequency Bands during the Continuous Feedback of Finger Force

作者：Zhang, Hang^*; Gao, Zhong-Zhan; Zang, Yu-Feng

来源：Biomed Research International, 2015, 2015: 273126.

DOI：10.1155/2015/273126

• GRIP FORCE
• SUSTAINED ATTENTION
• BRAIN ACTIVITY
• POWER-GRIP
• FUNCTIONAL CONNECTIVITY
• VISUAL FEEDBACK
• DEFAULT NETWORK
• BASAL GANGLIA
• PRECISION
• DEACTIVATION

Conventional functional magnetic resonance imaging (fMRI) studies on motor feedback employ periodical blocked paradigm which does not allow frequency analysis of brain activity. Here, we carried out an fMRI study by using a continuous paradigm, that is, continuous (8 min) feedback of finger force. Borrowing an analytic method widely used in resting-state fMRI studies, that is, regional homogeneity (ReHo), we compared the local synchronization in some subfrequency bands between real and sham feedback, and the subbands were defined as Slow-6 (0.0-0.01Hz), Slow-5 (0.01-0.027Hz), Slow-4 (0.027-0.073Hz), Slow-3 (0.073-0.198Hz), and Slow-2 (0.198-0.25Hz). Our results revealed that the five subfrequency bands of brain activity contributed to the changes of ReHo between real and sham feedback differently, and, more importantly, the changes in basal ganglia were only manifested in Slow-6, implicating the fact that ReHo in ultraslow band may be associated with the functional significance of BG, that is, motor control. These findings provide novel insights into the neural substrate underlying motor feedback, and properties of the ultraslow band of local synchronization deserve more attention in future explorations.

• 出版日期2015
• 单位中国科学院深圳先进技术研究院; 杭州师范大学