Unsymmetrical tetrasubstituted ureas from tertiary carbamoylimidazole: activation by AlMe3

作者:Velavan A; Sumathi S*; Balasubramanian K K
来源:Organic and Biomolecular Chemistry, 2012, 10(31): 6420-6431.
DOI:10.1039/c2ob25412c

摘要

An efficient and general method for the synthesis of unsymmetrical tetrasubstituted ureas from carbamoylimidazole is described. The conversion is achieved by the concurrent quarternization of the imidazole nitrogen and activation of amines with AlMe3.

  • 出版日期2012