Upper Gastrointestinal Bleeding in Chinese Children: A Multicenter 10-Year Retrospective Study

作者：Yu, Yi; Wang, Baoxiang; Yuan, Lan; Yang, Hui; Wang, Xinqiong; Xiao, Yuan; Mei, Hong; Xu, Chundi^*

来源：Clinical Pediatrics, 2016, 55(9): 838-843.

DOI：10.1177/0009922815611642

• upper gastrointestinal bleeding
• etiology
• esophagogastroduodenoscopy
• children
• NSAIDs

Objective. This study aims to analyze the clinical and endoscopic presentations of upper gastrointestinal bleeding (UGIB) in the Chinese children. Methods. A 10-year retrospective study was made on children with UGIB and undertaken esophagogastroduodenoscopy (EGD) from 4 tertiary referral centers in China. Results. Of the 1218 children studied, the bleeding source was found in 76.4%. Erosive gastritis was the most common endoscopic finding (33.5%), followed by duodenal ulcer (23.2%). The proportion of erosive gastritis decreased with age (correlation coefficient = -0.787), and duodenal ulcer increased with age (correlation coefficient = 0.958). The bleeding source was more likely to be determined in children having EGDs within 48 hours (80.6% vs 67.9%). Conclusions. In Chinese children with UGIB, erosive gastritis and duodenal ulcer were the leading causes, and their proportions varied with age. EGDs performed within 48 hours may improve the possibility of finding the source of bleeding.

• 出版日期2016-8
• 单位南京医科大学; 上海交通大学; 上海市闵行区中心医院