Pediatric reference intervals for immunoglobulin G and its subclasses with Siemens immunonephelometric assays

作者：Lepage Nathalie; Huang Shih Han S; Nieuwenhuys Ed; Filler Guido^*

来源：Clinical Biochemistry, 2010, 43(7-8): 694-696.

DOI：10.1016/j.clinbiochem.2010.02.003

• Immunoglobulin G
• Immunoglobulin G subclasses
• Nephelometric assay
• Pediatric reference intervals

Objective: To determine the pediatric reference intervals for the Dade Behring IgG subclass reagents.
Design and methods: Blood samples of healthy children and adolescents were analyzed to determine the level of immunoglobulin G (IgG) and the IgG subclass using the reagents of Dade Behring Marburg GmbH.
Results: The reference intervals categorized by age were reported from a total of 436 samples. There was an excellent correlation between the total IgG and the sum of the IgG subclasses.
Conclusions: Our data provide the missing pediatric reference intervals and enable the use of the Dade Behring nephelometric IgG subclass reagents in children and adolescents.

• 出版日期2010-5