A pyridoxal-based chemosensor for visual detection of copper ion and its application in bioimaging

作者：Yin Cai Xia; Qu Li Jun; Huo Fang Jun^*

来源：Chinese Chemical Letters, 2014, 25(9): 1230-1234.

DOI：10.1016/j.cclet.2014.06.017

• Pyridoxal-based
• Copper ion
• Chemosensor
• Bioimaging

A pyridoxal-based chemosensor was synthesized by reacting hydrazine hydrate and pyridoxal hydrochloride in ethanol and characterized by NMR and ESI-MS. The optical properties of the compound were investigated in a methanol: HEPES solution. The compound displayed selectivity for Cu2+, as evidenced by a colorless to yellow color change, which was characterized using UV-vis spectroscopy. The fluorescence of the compound can be quenched only by Cu2+, accompanying by a color change from blue to colorless. Furthermore, it can be used in bioimaging.

• 出版日期2014-9
• 单位山西大学; 中国科学院长春应用化学研究所