A reversal phenomenon of enantioface selectivity by the cooperative operation of two chiral catalysts

作者:Kawasaki Tsuneomi*; Wakushima Yuki; Asahina Mai; Shiozawa Kazuya; Kinoshita Tomoyuki; Lutz Francois; Soai Kenso
来源:Chemical communications, 2011, 47(18): 5277-5279.
DOI:10.1039/c1cc10136f

摘要

The reversal phenomenon of enantioface selectivity in the asymmetric addition of diisopropylzinc to aldehydes was observed by mixing two chiral beta-amino alcohol catalysts. The opposite enantiomeric product was formed on using a mixture of two chiral catalysts that possess individual enantioselectivity.